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Solution structure of carboxyl-terminal domain of DBP5P

Analyse Solution structure of carboxyl-terminal domain of DBP5P in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 2KBF
Type: protein
Length: 187 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: ATP-dependent RNA helicase DBP5
EC: 3.6.1.-
UniProt: P20449
Pockets: 2 · best druggability 0.53

Structure

solution nmr · 1 distinct chain · 39% helix, 13% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	ATP-dependent RNA helicase DBP5 (EC 3.6.1.-)	protein	187	39% helix, 13% strand	P20449

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	74	0.53	0.86	18	empty
2	63	0.41	0.80	19	empty

Compared structures

2KBF · solution structure of carboxyl-terminal domain of Dbp5p · the same entry in another collection · chain A against A, TM-score 1.00
P20449 · AlphaFold monomer V2.0 prediction for ATP-dependent RNA helicase DBP5 (P20449) · a predicted model of the same protein · chain A against A, TM-score 0.78

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P20449
Elsewhere: RCSB PDB 2KBF · PDBe 2KBF · UniProt P20449

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