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Structure of the core binding domain of SIGMA54

Analyse Structure of the core binding domain of SIGMA54 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB
2K9M
Type
protein
Length
130 residues
Chains
1
Method
solution nmr
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
RNA polymerase sigma factor rpon
UniProt
O66858
Pockets
2 · best druggability 0.51

Structure

solution nmr · 1 distinct chain · 54% helix, 2% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
ARNA polymerase sigma factor rponprotein13054% helix, 2% strandO66858

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
11110.510.8126empty
2760.400.7817empty

Compared structures

  • 2K9M · Structure of the Core Binding Domain of sigma54 · the same entry in another collection · chain A against A, TM-score 1.00

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