Research workbench
LC3 P62 complex structure
Analyse LC3 P62 complex structure in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 2K6Q
- Type
- protein
- Length
- 138 residues
- Chains
- 2
- Method
- solution nmr
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Microtubule-associated proteins 1A/1B light chain 3B; P62_PEPTIDE from sequestosome-1
- UniProt
- Q62625, O08623
- Pockets
- 1 · best druggability 0.46
Structure
solution nmr · 2 distinct chains · 23% helix, 20% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Microtubule-associated proteins 1A/1B light chain 3B | protein | 121 | 26% helix, 21% strand | Q62625 |
| B | P62_PEPTIDE from sequestosome-1 | protein | 17 | 0% helix, 12% strand | O08623 |
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 134 | 0.46 | 0.77 | 22 | empty |
Interfaces
1 interface between chains.
- A–B · 751 Ų buried · 11 hydrogen bonds · protein-protein
Compared structures
- 2K6Q · LC3 p62 complex structure · the same entry in another collection · chain A against A, TM-score 1.00
- Q62625 · AlphaFold monomer V2.0 prediction for microtubule-associated proteins 1A/1B light chain… · a predicted model of the same protein · chain A against A, TM-score 0.83
- O08623 · AlphaFold monomer V2.0 prediction for sequestosome-1 (O08623) · a predicted model of the same protein · chain B against A, TM-score 0.21
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q62625
- Every structure of UniProt O08623
- Elsewhere: RCSB PDB 2K6Q · PDBe 2K6Q · UniProt Q62625 · UniProt O08623
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