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PCBP2 KH1-KH2 domains

Analyse PCBP2 KH1-KH2 domains in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 2JZX
Type: protein
Length: 160 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: POLY(RC)-binding protein 2
UniProt: Q15366
Pockets: 3 · best druggability 0.73

Structure

solution nmr · 1 distinct chain · 49% helix, 26% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	POLY(RC)-binding protein 2	protein	160	49% helix, 26% strand	Q15366

Pockets

3 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	278	0.73	0.86	35	empty
2	131	0.68	0.89	25	empty
3	70	0.31	0.74	12	empty

Compared structures

2JZX · PCBP2 KH1-KH2 domains · the same entry in another collection · chain A against A, TM-score 1.00
Q15366 · AlphaFold monomer V2.0 prediction for POLY(RC)-binding protein 2 (Q15366) · a predicted model of the same protein · chain A against A, TM-score 0.85

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q15366
Elsewhere: RCSB PDB 2JZX · PDBe 2JZX · UniProt Q15366

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