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Structure of the fifth zinc finger of myelin transcription factor 1 in complex with rare DNA

Analyse Structure of the fifth zinc finger of myelin transcription factor 1 in complex… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 2JX1
Type: protein + DNA
Length: 57 residues
Chains: 3
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: DNA (5'- D(*DAP*DCP*DCP*DGP*DAP*DAP*DAP*DGP*DTP*DTP*DCP*DAP*DC)-3'); DNA (5'…
UniProt: Q8CFC2

Structure

solution nmr · 3 distinct chains · 0% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
B	DNA (5'- D(DAPDCPDCPDGPDAPDAPDAPDGPDTPDTPDCPDAP*DC)-3')	dna	13	—	—
C	DNA (5'- D(DGPDTPDGPDAPDAPDCPDTPDTPDTPDCPDGPDGP*DT)-3')	dna	13	—	—
A	Myelin transcription factor 1	protein	31	0% helix, 0% strand	Q8CFC2

Interfaces

3 interfaces between chains.

B–C · 606 Å² buried · 72 hydrogen bonds · nucleic-nucleic
B–A · 447 Å² buried · 22 hydrogen bonds · protein-nucleic
C–A · 355 Å² buried · 12 hydrogen bonds · protein-nucleic

Compared structures

2JX1 · Structure of the fifth zinc finger of Myelin Transcription Factor 1 in complex with RARE… · the same entry in another collection · chain B against B, TM-score 1.00
Q8CFC2 · AlphaFold monomer V2.0 prediction for myelin transcription factor 1 (Q8CFC2) · a predicted model of the same protein · chain A against A, TM-score 0.55

Analyse

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Every structure of UniProt Q8CFC2
Elsewhere: RCSB PDB 2JX1 · PDBe 2JX1 · UniProt Q8CFC2

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