Research workbench

Solution NMR structure of the protease-resistent domain of xenopus laevis EPABP2

Analyse Solution NMR structure of the protease-resistent domain of xenopus laevis EPABP2 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 2JWN
Type: protein
Length: 248 residues
Chains: 2
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Embryonic polyadenylate-binding protein 2-B
UniProt: Q6TY21
Pockets: 1 · best druggability 0.70

Structure

solution nmr · 1 distinct chain · 21% helix, 26% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	Embryonic polyadenylate-binding protein 2-B	protein	124	21% helix, 26% strand	Q6TY21

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	432	0.70	0.81	47	empty

Interfaces

1 interface between chains.

A–B · 1772 Å² buried · 26 hydrogen bonds · protein-protein

Compared structures

2JWN · Solution NMR structure of the protease-resistent domain of Xenopus laevis ePABP2 · the same entry in another collection · chain A against A, TM-score 1.00
Q6TY21 · AlphaFold monomer V2.0 prediction for embryonic polyadenylate-binding protein 2-B (Q6TY21) · a predicted model of the same protein · chain B against A, TM-score 0.66

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q6TY21
Elsewhere: RCSB PDB 2JWN · PDBe 2JWN · UniProt Q6TY21

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.