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A functional domain of a wnt signal protein

Analyse A functional domain of a wnt signal protein in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 2JTK
Type: protein
Length: 88 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Dickkopf-related protein 2
UniProt: Q9QYZ8
Pockets: 1 · best druggability 0.54

Structure

solution nmr · 1 distinct chain · 3% helix, 26% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Dickkopf-related protein 2	protein	88	3% helix, 26% strand	Q9QYZ8

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	194	0.54	0.79	21	empty

Modifications

Observed in the structure: 5 disulfide (disulfide).

Compared structures

2JTK · A functional domain of a Wnt signal protein · the same entry in another collection · chain A against A, TM-score 1.00
Q9QYZ8 · AlphaFold monomer V2.0 prediction for dickkopf-related protein 2 (Q9QYZ8) · a predicted model of the same protein · chain A against A, TM-score 0.63

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9QYZ8
Elsewhere: RCSB PDB 2JTK · PDBe 2JTK · UniProt Q9QYZ8

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