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NMR structure of immunosuppressory peptide containing cyclolinopeptide X and ANTENNAPEDIA(43-58) sequences

Analyse NMR structure of immunosuppressory peptide containing cyclolinopeptide X and… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 2JT9
Type: protein
Length: 21 residues
Chains: 2
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: 5-mer immunosuppressory peptide from cyclolinopeptide X; Modified 16-mer…
Ligands: ABU, ACA, NH2

Structure

solution nmr · 2 distinct chains · 14% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	5-mer immunosuppressory peptide from cyclolinopeptide X	protein	5	0% helix, 0% strand	—
B	Modified 16-mer immunosuppressory peptide from homeotic protein antennapedia	protein	16	19% helix, 0% strand	—

Ligands and binding sites

ABU · Gamma-amino-butanoic acid · ligand · chains A, B
ACA · 6-aminohexanoic acid · ligand · chains A, B
NH2 · Amino group · ion · chains B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Interfaces

1 interface between chains.

A–B · 224 Å² buried · 4 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 3 covalent, 3 modified (covalent ligand, nonstandard).

Compared structures

2JT9 · NMR structure of immunosuppressory peptide containing cyclolinopeptide X and… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Elsewhere: RCSB PDB 2JT9 · PDBe 2JT9

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