Research workbench

Solution NMR structure of human myeloid differentiation primary response (MYD88). northeast structural genomics target HR2869A

Analyse Solution NMR structure of human myeloid differentiation primary response… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 2JS7
Type: protein
Length: 160 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Myeloid differentiation primary response protein MYD88
UniProt: Q99836
Pockets: 2 · best druggability 0.46

Structure

solution nmr · 1 distinct chain · 34% helix, 14% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Myeloid differentiation primary response protein MYD88	protein	160	34% helix, 14% strand	Q99836

Pockets

2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	94	0.46	0.80	21	empty
2	112	0.41	0.76	21	empty

Compared structures

2JS7 · Solution NMR structure of human myeloid differentiation primary response (MyD88).… · the same entry in another collection · chain A against A, TM-score 1.00
Q99836 · AlphaFold monomer V2.0 prediction for myeloid differentiation primary response protein… · a predicted model of the same protein · chain A against A, TM-score 0.76

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q99836
Elsewhere: RCSB PDB 2JS7 · PDBe 2JS7 · UniProt Q99836

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.