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R21A spc-SH3:P41 complex

Analyse R21A spc-SH3:P41 complex in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 2JMA
Type: protein
Length: 72 residues
Chains: 2
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Spectrin alpha chain, brain; P41 peptide
UniProt: P07751
Ligands: ACE

Structure

solution nmr · 2 distinct chains · 4% helix, 39% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Spectrin alpha chain, brain	protein	62	5% helix, 45% strand	P07751
B	P41 peptide	protein	10	0% helix, 0% strand	—

Ligands and binding sites

ACE · Acetyl group · ligand · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Interfaces

1 interface between chains.

A–B · 459 Å² buried · 4 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 1 covalent (covalent ligand).

Compared structures

2JMA · R21A Spc-SH3:P41 complex · the same entry in another collection · chain A against A, TM-score 1.00
P07751 · AlphaFold monomer V2.0 prediction for spectrin alpha chain, non- erythrocytic 1 (P07751) · a predicted model of the same protein · chain A against A, TM-score 0.89

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P07751
Elsewhere: RCSB PDB 2JMA · PDBe 2JMA · UniProt P07751

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