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Crystal structure of rhogdi K135H,K138H,K141H mutant

Analyse Crystal structure of rhogdi K135H,K138H,K141H mutant in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 2JHS
Type: protein
Length: 137 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Rho GDP-dissociation inhibitor 1
UniProt: P52565
Pockets: 1 · best druggability 0.45

Structure

x-ray diffraction · 1 distinct chain · 5% helix, 56% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Rho GDP-dissociation inhibitor 1	protein	137	5% helix, 56% strand	P52565

Ligands and binding sites

FLC · Citrate anion · additive · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	102	0.45	0.79	17	empty

Compared structures

2JHS · Crystal structure of rhogdi K135H,K138H,K141H mutant · the same entry in another collection · chain A against A, TM-score 1.00
P52565 · AlphaFold monomer V2.0 prediction for rho GDP-dissociation inhibitor 1 (P52565) · a predicted model of the same protein · chain A against A, TM-score 0.98

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P52565
Elsewhere: RCSB PDB 2JHS · PDBe 2JHS · UniProt P52565

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