Research workbench
The structure of bluetongue virus VP4 reveals a multifunctional RNA-capping production-line
Analyse The structure of bluetongue virus VP4 reveals a multifunctional RNA-capping… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 2JHA
- Type
- protein
- Length
- 613 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- VP4 core protein
- UniProt
- P07132
- Ligands
- GUN, GP3
- Pockets
- 7 · best druggability 0.72
Structure
x-ray diffraction · 1 distinct chain · 33% helix, 17% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | VP4 core protein | protein | 613 | 33% helix, 17% strand | P07132 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
7 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 102 | 0.72 | 0.94 | 30 | empty |
| 2 | 241 | 0.55 | 0.77 | 34 | GUN |
| 3 | 265 | 0.54 | 0.76 | 25 | empty |
| 4 | 215 | 0.52 | 0.76 | 25 | empty |
| 5 | 115 | 0.40 | 0.75 | 14 | GUN |
Compared structures
- 2JHA · The structure of bluetongue virus VP4 reveals a multifunctional RNA- capping… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P07132
- Elsewhere: RCSB PDB 2JHA · PDBe 2JHA · UniProt P07132
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.