Research workbench
Crystal structure of human cytosolic 5'-nucleotidase III in complex with phosphate and magnesium
Analyse Crystal structure of human cytosolic 5'-nucleotidase III in complex with… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 2JGA
- Type
- protein
- Length
- 273 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Cytosolic 5'-nucleotidase III
- EC
- 3.1.3.5
- UniProt
- Q9H0P0
- Ligands
- MG, PO4
- Pockets
- 2 · best druggability 0.79
Structure
x-ray diffraction · 1 distinct chain · 46% helix, 18% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Cytosolic 5'-nucleotidase III (EC 3.1.3.5) | protein | 273 | 46% helix, 18% strand | Q9H0P0 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 563 | 0.79 | 0.85 | 48 | PO4, MG |
| 2 | 50 | 0.27 | 0.75 | 12 | empty |
Compared structures
- 2JGA · Crystal structure of human cytosolic 5'-nucleotidase III in complex with phosphate and… · the same entry in another collection · chain A against A, TM-score 1.00
- Q9H0P0 · AlphaFold monomer V2.0 prediction for cytosolic 5'-nucleotidase 3A (Q9H0P0) · a predicted model of the same protein · chain A against A, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9H0P0
- Elsewhere: RCSB PDB 2JGA · PDBe 2JGA · UniProt Q9H0P0
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