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Structure of strictosidine glucosidase
Analyse Structure of strictosidine glucosidase in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 2JF7
- Type
- protein
- Length
- 933 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Strictosidine-O-beta-D-glucosidase
- EC
- 3.2.1.105
- UniProt
- Q8GU20
- Pockets
- 5 · best druggability 0.76
Structure
x-ray diffraction · 2 distinct chains · 46% helix, 17% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Strictosidine-O-beta-D-glucosidase (EC 3.2.1.105) | protein | 467 | 46% helix, 17% strand | Q8GU20 |
| B | Strictosidine-O-beta-D-glucosidase (EC 3.2.1.105) | protein | 466 | 46% helix, 17% strand | Q8GU20 |
Pockets
5 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1131 | 0.76 | 0.79 | 99 | empty |
| 2 | 461 | 0.75 | 0.83 | 45 | empty |
| 3 | 467 | 0.73 | 0.82 | 46 | empty |
| 4 | 62 | 0.30 | 0.74 | 14 | empty |
| 5 | 60 | 0.28 | 0.74 | 15 | empty |
Interfaces
1 interface between chains.
- A–B · 727 Ų buried · 2 hydrogen bonds · protein-protein
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q8GU20
- Elsewhere: RCSB PDB 2JF7 · PDBe 2JF7 · UniProt Q8GU20
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