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Mycobacterium tuberculosis glutamyl-tRNA synthetase

Analyse Mycobacterium tuberculosis glutamyl-tRNA synthetase in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 2JA2
Type: protein
Length: 485 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Glutamyl-tRNA synthetase
EC: 6.1.1.17
UniProt: P0A636
Ligands: CL
Pockets: 1 · best druggability 0.66

Structure

x-ray diffraction · 1 distinct chain · 51% helix, 11% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Glutamyl-tRNA synthetase (EC 6.1.1.17)	protein	485	51% helix, 11% strand	P0A636

Ligands and binding sites

CL · Chloride ion · ion · chains A
ACT · Acetate ion · additive · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	362	0.66	0.80	48	ACT, CL

Compared structures

2JA2 · Mycobacterium tuberculosis glutamyl-tRNA synthetase · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P0A636
Elsewhere: RCSB PDB 2JA2 · PDBe 2JA2 · UniProt P0A636

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