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Solution structure of the A4 domain of blood coagulation factor XI

Analyse Solution structure of the A4 domain of blood coagulation factor XI in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 2J8J
Type: protein
Length: 180 residues
Chains: 2
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Coagulation factor XI
EC: 3.4.21.27
UniProt: P03951

Structure

solution nmr · 1 distinct chain · 14% helix, 34% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	Coagulation factor XI (EC 3.4.21.27)	protein	90	14% helix, 34% strand	P03951

Interfaces

1 interface between chains.

A–B · 886 Å² buried · 12 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 7 disulfide (disulfide).

Compared structures

2J8J · Solution Structure of the A4 Domain of Blood Coagulation Factor XI · the same entry in another collection · chain A against A, TM-score 1.00
P03951 · AlphaFold monomer V2.0 prediction for coagulation factor XI (P03951) · a predicted model of the same protein · chain A against A, TM-score 0.63

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P03951
Elsewhere: RCSB PDB 2J8J · PDBe 2J8J · UniProt P03951

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