Research workbench
Crystal structure of ap endonuclease lmap from leishmania major
Analyse Crystal structure of ap endonuclease lmap from leishmania major in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 2J63
- Type
- protein
- Length
- 666 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Ap-endonuclease
- EC
- 4.2.99.18
- UniProt
- O15922
- Pockets
- 4 · best druggability 0.52
Structure
x-ray diffraction · 1 distinct chain · 28% helix, 23% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Ap-endonuclease (EC 4.2.99.18) | protein | 333 | 28% helix, 23% strand | O15922 |
Pockets
4 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 249 | 0.52 | 0.75 | 32 | empty |
| 2 | 220 | 0.49 | 0.75 | 30 | empty |
| 3 | 64 | 0.39 | 0.79 | 14 | empty |
| 4 | 51 | 0.33 | 0.78 | 14 | empty |
Compared structures
- 2J63 · Crystal structure of AP endonuclease LMAP from Leishmania major · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O15922
- Elsewhere: RCSB PDB 2J63 · PDBe 2J63 · UniProt O15922
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