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Crystal structure of trypanosoma cruzi arginine kinase

Analyse Crystal structure of trypanosoma cruzi arginine kinase in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 2J1Q
Type: protein
Length: 339 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Arginine kinase
EC: 2.7.3.3
UniProt: O96507
Pockets: 3 · best druggability 0.33

Structure

x-ray diffraction · 1 distinct chain · 40% helix, 18% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Arginine kinase (EC 2.7.3.3)	protein	339	40% helix, 18% strand	O96507

Ligands and binding sites

GOL · Glycerol · additive · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

3 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	98	0.33	0.73	23	empty
2	84	0.33	0.74	20	empty
3	59	0.32	0.76	13	empty

Compared structures

2J1Q · Crystal structure of Trypanosoma cruzi arginine kinase · the same entry in another collection · chain A against A, TM-score 1.00
O96507 · AlphaFold monomer V2.0 prediction for arginine kinase (O96507) · a predicted model of the same protein · chain A against A, TM-score 0.99

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt O96507
Elsewhere: RCSB PDB 2J1Q · PDBe 2J1Q · UniProt O96507

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