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The crystal structure of iron, sulfur-dependent L-serine dehydratase from legionella pneumophila subsp. pneumophila
Analyse The crystal structure of iron, sulfur-dependent L-serine dehydratase from… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 2IQQ
- Type
- protein
- Length
- 290 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Iron, sulfur-dependent L-serine dehydratase
- EC
- 4.3.1.17
- UniProt
- Q5ZXE1
- Ligands
- MG
- Pockets
- 2 · best druggability 0.58
Structure
x-ray diffraction · 1 distinct chain · 33% helix, 26% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Iron, sulfur-dependent L-serine dehydratase (EC 4.3.1.17) | protein | 145 | 33% helix, 26% strand | Q5ZXE1 |
Ligands and binding sites
- MG · Magnesium ion · metal · 2 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 171 | 0.58 | 0.82 | 27 | empty |
| 2 | 145 | 0.45 | 0.76 | 27 | empty |
Interfaces
1 interface between chains.
- A–B · 584 Ų buried · 6 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 8 modified (engineered).
Compared structures
- 2IQQ · The Crystal Structure of Iron, Sulfur-Dependent L-serine dehydratase from Legionella… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q5ZXE1
- Elsewhere: RCSB PDB 2IQQ · PDBe 2IQQ · UniProt Q5ZXE1
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