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Unliganded crystal structure of the uridine phosphorylase from salmonella typhimurium at 1.90 a resolution

Analyse Unliganded crystal structure of the uridine phosphorylase from salmonella… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 2IQ5
Type: protein
Length: 475 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Uridine phosphorylase
EC: 2.4.2.3
UniProt: P0A1F6
Pockets: 3 · best druggability 0.72

Structure

x-ray diffraction · 2 distinct chains · 33% helix, 30% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Uridine phosphorylase (EC 2.4.2.3)	protein	250	34% helix, 29% strand	P0A1F6
B	Uridine phosphorylase (EC 2.4.2.3)	protein	225	32% helix, 32% strand	P0A1F6

Pockets

3 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	495	0.72	0.81	44	empty
2	385	0.66	0.80	53	empty
3	78	0.33	0.75	26	empty

Interfaces

1 interface between chains.

A–B · 1540 Å² buried · 19 hydrogen bonds · protein-protein

Compared structures

2IQ5 · Unliganded Crystal Structure of the Uridine Phosphorylase from Salmonella Typhimurium at… · the same entry in another collection · chain A against A, TM-score 1.00

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Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P0A1F6
Elsewhere: RCSB PDB 2IQ5 · PDBe 2IQ5 · UniProt P0A1F6

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