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Crystal structure of human PPM1K

Analyse Crystal structure of human PPM1K in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 2IQ1
Type: protein
Length: 257 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Protein phosphatase 2C kappa, PPM1K
UniProt: Q8N3J5
Ligands: MG
Pockets: 1 · best druggability 0.40

Structure

x-ray diffraction · 1 distinct chain · 32% helix, 31% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Protein phosphatase 2C kappa, PPM1K	protein	257	32% helix, 31% strand	Q8N3J5

Ligands and binding sites

MG · Magnesium ion · metal · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	104	0.40	0.77	21	MG

Compared structures

2IQ1 · Crystal structure of human PPM1K · the same entry in another collection · chain A against A, TM-score 1.00
Q8N3J5 · AlphaFold monomer V2.0 prediction for protein phosphatase 1K, mitochondrial (Q8N3J5) · a predicted model of the same protein · chain A against A, TM-score 0.99

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q8N3J5
Elsewhere: RCSB PDB 2IQ1 · PDBe 2IQ1 · UniProt Q8N3J5

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