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Solution structure of P45 death domain

Analyse Solution structure of P45 death domain in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB
2IB1
Type
protein
Length
91 residues
Chains
1
Method
solution nmr
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
Death domain containing membrane protein nradd
UniProt
Q8CJ26
Pockets
1 · best druggability 0.70

Structure

solution nmr · 1 distinct chain · 49% helix, 0% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
ADeath domain containing membrane protein nraddprotein9149% helix, 0% strandQ8CJ26

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
11650.700.8824empty

Compared structures

  • 2IB1 · Solution structure of p45 Death Domain · the same entry in another collection · chain A against A, TM-score 1.00
  • Q8CJ26 · AlphaFold monomer V2.0 prediction for death domain-containing membrane protein nradd… · a predicted model of the same protein · chain A against A, TM-score 0.65

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