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Crystal structure of anopheles gambiae SER/THR phosphatase complexed with ZN2+

Analyse Crystal structure of anopheles gambiae SER/THR phosphatase complexed with ZN2+ in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 2I0O
Type: protein
Length: 287 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: SER/THR phosphatase
UniProt: Q7PP01
Ligands: ZN
Pockets: 1 · best druggability 0.27

Structure

x-ray diffraction · 1 distinct chain · 32% helix, 32% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	SER/THR phosphatase	protein	287	32% helix, 32% strand	Q7PP01

Ligands and binding sites

ZN · Zinc ion · metal · 6 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	63	0.27	0.73	17	empty

Compared structures

2I0O · Crystal structure of Anopheles gambiae Ser/Thr phosphatase complexed with Zn2+ · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q7PP01
Elsewhere: RCSB PDB 2I0O · PDBe 2I0O · UniProt Q7PP01

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