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Crystal structure of the glutaminyl-tRNA synthetase from deinococcus radiodurans

Analyse Crystal structure of the glutaminyl-tRNA synthetase from deinococcus radiodurans in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 2HZ7
Type: protein
Length: 556 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Glutaminyl-tRNA synthetase
EC: 6.1.1.18
UniProt: P56926
Pockets: 4 · best druggability 0.82

Structure

x-ray diffraction · 1 distinct chain · 31% helix, 26% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Glutaminyl-tRNA synthetase (EC 6.1.1.18)	protein	556	31% helix, 26% strand	P56926

Pockets

4 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	209	0.82	0.95	32	empty
2	697	0.70	0.77	62	empty
3	52	0.47	0.85	15	empty
4	97	0.35	0.74	16	empty

Compared structures

2HZ7 · Crystal structure of the Glutaminyl-tRNA synthetase from Deinococcus radiodurans · the same entry in another collection · chain A against A, TM-score 1.00
P56926 · AlphaFold monomer V2.0 prediction for glutamine--tRNA ligase (P56926) · a predicted model of the same protein · chain A against A, TM-score 0.96

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P56926
Elsewhere: RCSB PDB 2HZ7 · PDBe 2HZ7 · UniProt P56926

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