Research workbench
Crystal structure of a putative mutarotase (yead) from salmonella typhimurium in monoclinic form
Analyse Crystal structure of a putative mutarotase (yead) from salmonella typhimurium… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 2HTB
- Type
- protein
- Length
- 1,183 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Putative enzyme related to aldose 1-epimerase
- EC
- 5.1.3.-
- UniProt
- Q8ZPV9
- Pockets
- 7 · best druggability 0.82
Structure
x-ray diffraction · 2 distinct chains · 9% helix, 50% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B, D | Putative enzyme related to aldose 1-epimerase (EC 5.1.3.-) | protein | 296 | 9% helix, 49% strand | Q8ZPV9 |
| C | Putative enzyme related to aldose 1-epimerase (EC 5.1.3.-) | protein | 295 | 9% helix, 51% strand | Q8ZPV9 |
Pockets
7 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1082 | 0.82 | 0.83 | 87 | empty |
| 2 | 296 | 0.53 | 0.74 | 48 | empty |
| 3 | 301 | 0.52 | 0.74 | 45 | empty |
| 4 | 117 | 0.43 | 0.77 | 21 | empty |
| 5 | 123 | 0.43 | 0.76 | 25 | empty |
Interfaces
4 interfaces between chains.
- A–C · 626 Ų buried · 7 hydrogen bonds · protein-protein
- A–B · 508 Ų buried · 15 hydrogen bonds · protein-protein
- C–D · 504 Ų buried · 12 hydrogen bonds · protein-protein
- A–D · 141 Ų buried · 1 hydrogen bond · protein-protein
Compared structures
- 2HTB · Crystal Structure of a putative mutarotase (YeaD) from Salmonella typhimurium in… · the same entry in another collection · chain A against A, TM-score 1.00
- Q8ZPV9 · AlphaFold monomer V2.0 prediction for putative glucose-6-phosphate 1-epimerase (Q8ZPV9) · a predicted model of the same protein · chain C against A, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q8ZPV9
- Elsewhere: RCSB PDB 2HTB · PDBe 2HTB · UniProt Q8ZPV9
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.