Research workbench
Functional characterization of pseudomonas aeruginosa pilf
Analyse Functional characterization of pseudomonas aeruginosa pilf in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 2HO1
- Type
- protein
- Length
- 443 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Type 4 fimbrial biogenesis protein pilf
- UniProt
- Q9HXJ2
- Pockets
- 3 · best druggability 0.64
Structure
x-ray diffraction · 2 distinct chains · 76% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Type 4 fimbrial biogenesis protein pilf | protein | 222 | 76% helix, 0% strand | Q9HXJ2 |
| B | Type 4 fimbrial biogenesis protein pilf | protein | 221 | 76% helix, 0% strand | Q9HXJ2 |
Pockets
3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 184 | 0.64 | 0.84 | 28 | empty |
| 2 | 99 | 0.40 | 0.77 | 21 | empty |
| 3 | 105 | 0.38 | 0.75 | 18 | empty |
Interfaces
1 interface between chains.
- A–B · 794 Ų buried · 15 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 6 modified (engineered).
Compared structures
- 2HO1 · Functional Characterization of Pseudomonas Aeruginosa pilF · the same entry in another collection · chain A against A, TM-score 1.00
- Q9HXJ2 · AlphaFold monomer V2.0 prediction for type IV pilus assembly protein pilf (Q9HXJ2) · a predicted model of the same protein · chain A against A, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9HXJ2
- Elsewhere: RCSB PDB 2HO1 · PDBe 2HO1 · UniProt Q9HXJ2
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.