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Crystal structure of N-terminal domain of ribosomal protein L9 (NTL9) K12M

Analyse Crystal structure of N-terminal domain of ribosomal protein L9 (NTL9) K12M in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB
2HBA
Type
protein
Length
104 residues
Chains
2
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
50S ribosomal protein L9
UniProt
P02417
Ligands
ZN, CL
Pockets
1 · best druggability 0.40

Structure

x-ray diffraction · 1 distinct chain · 37% helix, 23% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
A, B50S ribosomal protein L9protein5237% helix, 23% strandP02417

Ligands and binding sites

  • ZN · Zinc ion · metal · 8 copies · chains A, B
  • CL · Chloride ion · ion · 10 copies · chains A, B
  • IMD · Imidazole · additive

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
1820.400.7817empty

Interfaces

1 interface between chains.

  • A–B · 602 Ų buried · 4 hydrogen bonds · protein-protein

Compared structures

  • 2HBA · Crystal Structure of N-terminal Domain of Ribosomal Protein L9 (NTL9) K12M · the same entry in another collection · chain A against A, TM-score 1.00
  • P02417 · AlphaFold monomer V2.0 prediction for 50S ribosomal protein L9 (P02417) · a predicted model of the same protein · chain A against A, TM-score 0.85

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