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Crystal structure of the rho-GTPase binding domain of ypka

Analyse Crystal structure of the rho-GTPase binding domain of ypka in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 2H7O
Type: protein
Length: 270 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Protein kinase ypka
UniProt: Q05608
Pockets: 3 · best druggability 0.54

Structure

x-ray diffraction · 1 distinct chain · 86% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Protein kinase ypka	protein	270	86% helix, 0% strand	Q05608

Pockets

3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	262	0.54	0.76	32	empty
2	55	0.38	0.80	15	empty
3	52	0.33	0.78	16	empty

Compared structures

2H7O · Crystal structure of the Rho-GTPase binding domain of YpkA · the same entry in another collection · chain A against A, TM-score 1.00
Q05608 · AlphaFold monomer V2.0 prediction for protein kinase ypka (Q05608) · a predicted model of the same protein · chain A against A, TM-score 0.81

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q05608
Elsewhere: RCSB PDB 2H7O · PDBe 2H7O · UniProt Q05608

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