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Solution structure of the first neat domain of isdh

Analyse Solution structure of the first neat domain of isdh in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 2H3K
Type: protein
Length: 144 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Haptoglobin-binding surface anchored protein
UniProt: Q6G8J7
Pockets: 2 · best druggability 0.71

Structure

solution nmr · 1 distinct chain · 5% helix, 36% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Haptoglobin-binding surface anchored protein	protein	144	5% helix, 36% strand	Q6G8J7

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	265	0.71	0.85	32	empty
2	57	0.42	0.82	14	empty

Compared structures

2H3K · Solution Structure of the first NEAT domain of IsdH · the same entry in another collection · chain A against A, TM-score 1.00
Q6G8J7 · AlphaFold monomer V2.0 prediction for iron-regulated surface determinant protein H… · a predicted model of the same protein · chain A against A, TM-score 0.87

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q6G8J7
Elsewhere: RCSB PDB 2H3K · PDBe 2H3K · UniProt Q6G8J7

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