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Crystal structure of 4-stranded oxytricha telomeric DNA

Analyse Crystal structure of 4-stranded oxytricha telomeric DNA in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB
1D59
Type
DNA
Length
48 nucleotides
Chains
4
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
DNA (5'-D(*GP*GP*GP*GP*TP*TP*TP*TP*GP*GP*GP*G)- 3')
Pockets
1 · best druggability 0.34

Structure

x-ray diffraction · 1 distinct chain.

ChainMoleculeTypeResiduesSecondary structureUniProt
A, B, C, DDNA (5'-D(*GP*GP*GP*GP*TP*TP*TP*TP*GP*GP*GP*G)- 3')dna12——

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
11040.340.7412empty

Interfaces

4 interfaces between chains.

  • A–B · 593 Ų buried · 47 hydrogen bonds · nucleic-nucleic
  • C–D · 576 Ų buried · 33 hydrogen bonds · nucleic-nucleic
  • A–C · 76 Ų buried · 1 hydrogen bond · nucleic-nucleic
  • B–D · 28 Ų buried · 0 hydrogen bonds · nucleic-nucleic

Compared structures

  • 1D59 · Crystal structure of 4-stranded oxytricha telomeric DNA · the same entry in another collection · chain A against A, TM-score 1.00

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