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29-mer fragment of human srp RNA helix 6

Analyse 29-mer fragment of human srp RNA helix 6 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB
1D4R
Type
RNA
Length
85 nucleotides
Chains
3
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
29-mer of modified srp RNA helix 6
Ligands
MG
Pockets
1 · best druggability 0.60

Structure

x-ray diffraction · 2 distinct chains.

ChainMoleculeTypeResiduesSecondary structureUniProt
A29-mer of modified srp RNA helix 6rna29——
B, C29-mer of modified srp RNA helix 6rna28——

Ligands and binding sites

  • MG · Magnesium ion · metal · 5 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
15650.600.7531MG

Interfaces

2 interfaces between chains.

  • A–B · 1326 Ų buried · 148 hydrogen bonds · nucleic-nucleic
  • B–C · 88 Ų buried · 1 hydrogen bond · nucleic-nucleic

Modifications

Observed in the structure: 4 modified (nucleotide modification).

Compared structures

  • 1D4R · 29-mer fragment of human srp rna helix 6 · the same entry in another collection · chain A against A, TM-score 1.00

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