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Solution structure of human apo SCO1

Analyse Solution structure of human apo SCO1 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 2GVP
Type: protein
Length: 173 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: SCO1 protein homolog, mitochondrial
UniProt: O75880
Pockets: 2 · best druggability 0.72

Structure

solution nmr · 1 distinct chain · 27% helix, 18% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	SCO1 protein homolog, mitochondrial	protein	173	27% helix, 18% strand	O75880

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	382	0.72	0.83	36	empty
2	97	0.41	0.77	14	empty

Compared structures

2GVP · Solution structure of Human apo Sco1 · the same entry in another collection · chain A against A, TM-score 1.00
O75880 · AlphaFold monomer V2.0 prediction for protein SCO1 homolog, mitochondrial (O75880) · a predicted model of the same protein · chain A against A, TM-score 0.80

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt O75880
Elsewhere: RCSB PDB 2GVP · PDBe 2GVP · UniProt O75880

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