Research workbench
Crystal structure of recombinant type I fructose-1,6-bisphosphatase from escherichia COLI complexed with sulfate ions
Analyse Crystal structure of recombinant type I fructose-1,6-bisphosphatase from… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 2GQ1
- Type
- protein
- Length
- 310 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Fructose-1,6-bisphosphatase
- EC
- 3.1.3.11
- UniProt
- P0A993
- Ligands
- SO4
- Pockets
- 2 · best druggability 0.42
Structure
x-ray diffraction · 1 distinct chain · 39% helix, 25% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Fructose-1,6-bisphosphatase (EC 3.1.3.11) | protein | 310 | 39% helix, 25% strand | P0A993 |
Ligands and binding sites
- SO4 · Sulfate ion · ion · 7 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 130 | 0.42 | 0.76 | 22 | SO4 |
| 2 | 96 | 0.40 | 0.77 | 21 | empty |
Modifications
Observed in the structure: 6 modified (engineered).
Compared structures
- 2GQ1 · Crystal Structure of Recombinant Type I Fructose-1,6-bisphosphatase from Escherichia coli… · the same entry in another collection · chain A against A, TM-score 1.00
- P0A993 · AlphaFold monomer V2.0 prediction for fructose-1,6-bisphosphatase class 1 (P0A993) · a predicted model of the same protein · chain A against A, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P0A993
- Elsewhere: RCSB PDB 2GQ1 · PDBe 2GQ1 · UniProt P0A993
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