Research workbench

X-ray crystal structure of mycobacterium tuberculosis beta-ketoacyl acyl carrier protein synthase II (mtkasb)

Analyse X-ray crystal structure of mycobacterium tuberculosis beta-ketoacyl acyl… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 2GP6
Type: protein
Length: 830 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: 3-oxoacyl-[acyl-carrier-protein] synthase 2
EC: 2.3.1.41
UniProt: P63456
Pockets: 12 · best druggability 0.80

Structure

x-ray diffraction · 1 distinct chain · 33% helix, 19% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	3-oxoacyl-[acyl-carrier-protein] synthase 2 (EC 2.3.1.41)	protein	415	33% helix, 19% strand	P63456

Pockets

12 pockets found on a 1 Å grid, 6 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	432	0.80	0.87	68	empty
2	125	0.79	0.97	30	empty
3	101	0.71	0.94	30	empty
4	116	0.68	0.90	32	empty
5	172	0.59	0.82	27	empty

Interfaces

1 interface between chains.

A–B · 3130 Å² buried · 32 hydrogen bonds · protein-protein

Compared structures

2GP6 · X-ray crystal structure of Mycobacterium tuberculosis beta-ketoacyl acyl carrier protein… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P63456
Elsewhere: RCSB PDB 2GP6 · PDBe 2GP6 · UniProt P63456

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.