Research workbench
Crystal structure of tetrameric biodegradative threonine deaminase (tdcb) from salmonella typhimurium in complex with cmp at 2.5A resolution (hexagonal form)
Analyse Crystal structure of tetrameric biodegradative threonine deaminase (tdcb) from… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 2GN2
- Type
- protein
- Length
- 326 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Threonine dehydratase catabolic
- EC
- 4.3.1.19
- UniProt
- P11954
- Ligands
- C5P, NA
- Pockets
- 3 · best druggability 0.60
Structure
x-ray diffraction · 1 distinct chain · 51% helix, 15% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Threonine dehydratase catabolic (EC 4.3.1.19) | protein | 326 | 51% helix, 15% strand | P11954 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 362 | 0.60 | 0.76 | 29 | empty |
| 2 | 61 | 0.36 | 0.78 | 13 | empty |
| 3 | 53 | 0.32 | 0.77 | 13 | empty |
Modifications
Observed in the structure: 1 modified (cofactor).
Compared structures
- 2GN2 · Crystal structure of tetrameric biodegradative threonine deaminase (TdcB) from Salmonella… · the same entry in another collection · chain A against A, TM-score 1.00
- P11954 · AlphaFold monomer V2.0 prediction for L-threonine dehydratase catabolic tdcb (P11954) · a predicted model of the same protein · chain A against A, TM-score 0.98
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P11954
- Elsewhere: RCSB PDB 2GN2 · PDBe 2GN2 · UniProt P11954
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.