Research workbench
Crystal structure of D,D-heptose 1.7-bisphosphate phosphatase from E. COLI.
Analyse Crystal structure of D,D-heptose 1.7-bisphosphate phosphatase from E. COLI. in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 2GMW
- Type
- protein
- Length
- 366 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- D,D-heptose 1,7-bisphosphate phosphatase
- EC
- 3.1.3.-
- UniProt
- P63228
- Ligands
- ZN
- Pockets
- 2 · best druggability 0.45
Structure
x-ray diffraction · 2 distinct chains · 40% helix, 19% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | D,D-heptose 1,7-bisphosphate phosphatase (EC 3.1.3.-) | protein | 182 | 41% helix, 19% strand | P63228 |
| B | D,D-heptose 1,7-bisphosphate phosphatase (EC 3.1.3.-) | protein | 184 | 40% helix, 19% strand | P63228 |
Ligands and binding sites
- ZN · Zinc ion · metal · 2 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 103 | 0.45 | 0.79 | 18 | empty |
| 2 | 114 | 0.43 | 0.77 | 20 | empty |
Compared structures
- 2GMW · Crystal Structure of D,D-heptose 1.7-bisphosphate phosphatase from E. Coli. · the same entry in another collection · chain A against A, TM-score 1.00
- P63228 · AlphaFold monomer V2.0 prediction for D-glycero-beta-D-manno- heptose-1,7-bisphosphate… · a predicted model of the same protein · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P63228
- Elsewhere: RCSB PDB 2GMW · PDBe 2GMW · UniProt P63228
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