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Crystal structure of triplex DNA

Analyse Crystal structure of triplex DNA in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB
1D3R
Type
DNA
Length
41 nucleotides
Chains
4
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
DNA (5'-D(*CP*(BRU)P*CP*CP*(BRU)P*CP*CP*GP*CP*GP*CP*G)-3'); DNA…

Structure

x-ray diffraction · 3 distinct chains.

ChainMoleculeTypeResiduesSecondary structureUniProt
A, CDNA (5'-D(*CP*(BRU)P*CP*CP*(BRU)P*CP*CP*GP*CP*GP*CP*G)-3')dna12——
BDNA (5'-D(*CP*GP*CP*GP*CP*GP*GP*AP*G)-3')dna9——
DDNA (5'-D(*CP*GP*CP*GP*CP*GP*GP*AP*G)-3')dna8——

Interfaces

6 interfaces between chains.

  • C–D · 397 Ų buried · 34 hydrogen bonds · nucleic-nucleic
  • A–B · 381 Ų buried · 33 hydrogen bonds · nucleic-nucleic
  • A–D · 254 Ų buried · 13 hydrogen bonds · nucleic-nucleic
  • B–C · 253 Ų buried · 12 hydrogen bonds · nucleic-nucleic
  • A–C · 102 Ų buried · 0 hydrogen bonds · nucleic-nucleic

Modifications

Observed in the structure: 4 modified (nucleotide modification).

Compared structures

  • 1D3R · Crystal structure of triplex DNA · the same entry in another collection · chain A against A, TM-score 1.00

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