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Crystal structure of mlta from E. COLI

Analyse Crystal structure of mlta from E. COLI in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 2GAE
Type: protein
Length: 333 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Membrane-bound lytic murein transglycosylase a
EC: 3.2.1.-
UniProt: P0A935
Pockets: 3 · best druggability 0.70

Structure

x-ray diffraction · 1 distinct chain · 27% helix, 29% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Membrane-bound lytic murein transglycosylase a (EC 3.2.1.-)	protein	333	27% helix, 29% strand	P0A935

Pockets

3 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	659	0.70	0.78	80	empty
2	62	0.52	0.87	20	empty
3	69	0.51	0.85	25	empty

Compared structures

2GAE · Crystal structure of MltA from E. coli · the same entry in another collection · chain A against A, TM-score 1.00
P0A935 · AlphaFold monomer V2.0 prediction for membrane-bound lytic murein transglycosylase a… · a predicted model of the same protein · chain A against A, TM-score 0.81

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P0A935
Elsewhere: RCSB PDB 2GAE · PDBe 2GAE · UniProt P0A935

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