Research workbench

Yeast frataxin

Analyse Yeast frataxin in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 2GA5
Type: protein
Length: 123 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Frataxin homolog, mitochondrial
UniProt: Q07540
Pockets: 2 · best druggability 0.58

Structure

solution nmr · 1 distinct chain · 31% helix, 26% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Frataxin homolog, mitochondrial	protein	123	31% helix, 26% strand	Q07540

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	263	0.58	0.78	36	empty
2	79	0.33	0.74	13	empty

Compared structures

2GA5 · yeast frataxin · the same entry in another collection · chain A against A, TM-score 1.00
Q07540 · AlphaFold monomer V2.0 prediction for frataxin homolog, mitochondrial (Q07540) · a predicted model of the same protein · chain A against A, TM-score 0.70

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q07540
Elsewhere: RCSB PDB 2GA5 · PDBe 2GA5 · UniProt Q07540

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