Research workbench
Crystal structure of the complex of sheep signalling glycoprotein with chitin trimer at 3.0A resolution
Analyse Crystal structure of the complex of sheep signalling glycoprotein with chitin… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 2G41
- Type
- protein
- Length
- 361 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Signal processing protein
- UniProt
- Q6TMG6
- Ligands
- NAG, BMA
- Pockets
- 3 · best druggability 0.60
Structure
x-ray diffraction · 1 distinct chain · 37% helix, 23% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Signal processing protein | protein | 361 | 37% helix, 23% strand | Q6TMG6 |
Ligands and binding sites
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · sugar · 5 copies · chains A
- BMA · beta-D-mannopyranose · sugar
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
3 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 305 | 0.60 | 0.78 | 42 | NAG |
| 2 | 283 | 0.57 | 0.77 | 42 | empty |
| 3 | 74 | 0.36 | 0.77 | 18 | empty |
Modifications
Observed in the structure: 2 disulfide, 1 glycan (disulfide, N-glycosylation).
Compared structures
- 2G41 · Crystal structure of the complex of sheep signalling glycoprotein with chitin trimer at… · the same entry in another collection · chain A against A, TM-score 1.00
- Q6TMG6 · AlphaFold monomer V2.0 prediction for chitinase-3-like protein 1 (Q6TMG6) · a predicted model of the same protein · chain A against A, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q6TMG6
- Elsewhere: RCSB PDB 2G41 · PDBe 2G41 · UniProt Q6TMG6
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