Research workbench
Crystal structure of a putative sugar isomerase (LMO2234) from listeria monocytogenes at 1.70 a resolution
Analyse Crystal structure of a putative sugar isomerase (LMO2234) from listeria… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 2G0W
- Type
- protein
- Length
- 560 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- LMO2234 protein
- UniProt
- Q4EPT5
- Ligands
- MG
- Pockets
- 5 · best druggability 0.57
Structure
x-ray diffraction · 2 distinct chains · 48% helix, 17% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | LMO2234 protein | protein | 275 | 49% helix, 16% strand | Q4EPT5 |
| B | LMO2234 protein | protein | 285 | 46% helix, 18% strand | Q4EPT5 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
5 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 131 | 0.57 | 0.83 | 23 | empty |
| 2 | 91 | 0.54 | 0.84 | 21 | empty |
| 3 | 108 | 0.51 | 0.82 | 19 | empty |
| 4 | 188 | 0.45 | 0.74 | 19 | empty |
| 5 | 50 | 0.29 | 0.75 | 13 | empty |
Interfaces
1 interface between chains.
- A–B · 124 Ų buried · 0 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 13 modified (engineered).
Compared structures
- 2G0W · Crystal structure of a putative sugar isomerase (LMO2234) from listeria monocytogenes at… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q4EPT5
- Elsewhere: RCSB PDB 2G0W · PDBe 2G0W · UniProt Q4EPT5
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