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Solution structure of the 2'-5' RNA ligase-like protein from pyrococcus furiosus

Analyse Solution structure of the 2'-5' RNA ligase-like protein from pyrococcus furiosus in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB
2FYH
Type
protein
Length
190 residues
Chains
1
Method
solution nmr
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
Putative integral membrane transport protein
UniProt
Q8U4Q3
Pockets
3 · best druggability 0.71

Structure

solution nmr · 1 distinct chain · 31% helix, 36% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
APutative integral membrane transport proteinprotein19031% helix, 36% strandQ8U4Q3

Pockets

3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
1700.710.9518empty
21960.480.7527empty
31320.410.7518empty

Compared structures

  • 2FYH · Solution structure of the 2'-5' RNA ligase-like protein from Pyrococcus furiosus · the same entry in another collection · chain A against A, TM-score 1.00
  • Q8U4Q3 · AlphaFold monomer V2.0 prediction for RNA 2',3'-cyclic phosphodiesterase (Q8U4Q3) · a predicted model of the same protein · chain A against A, TM-score 0.87

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