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Crystal structure of yeast TIM44

Analyse Crystal structure of yeast TIM44 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 2FXT
Type: protein
Length: 192 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Import inner membrane translocase subunit TIM44
UniProt: Q01852
Pockets: 4 · best druggability 0.44

Structure

x-ray diffraction · 1 distinct chain · 38% helix, 25% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Import inner membrane translocase subunit TIM44	protein	192	38% helix, 25% strand	Q01852

Pockets

4 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	86	0.44	0.80	14	empty
2	52	0.32	0.77	11	empty
3	59	0.31	0.76	16	empty
4	68	0.29	0.73	21	empty

Compared structures

2FXT · Crystal Structure of Yeast Tim44 · the same entry in another collection · chain A against A, TM-score 1.00
Q01852 · AlphaFold monomer V2.0 prediction for mitochondrial import inner membrane translocase… · a predicted model of the same protein · chain A against A, TM-score 0.92

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q01852
Elsewhere: RCSB PDB 2FXT · PDBe 2FXT · UniProt Q01852

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