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Structure of pure (N5-carboxyaminoimidazole ribonucleotide mutase) H89G from the acidophilic bacterium acetobacter aceti, at pH 8

Analyse Structure of pure (N5-carboxyaminoimidazole ribonucleotide mutase) H89G from… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 2FW8
Type: protein
Length: 319 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: N5-carboxyaminoimidazole ribonucleotide mutase
UniProt: Q2QJL3
Pockets: 2 · best druggability 0.32

Structure

x-ray diffraction · 2 distinct chains · 48% helix, 15% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	N5-carboxyaminoimidazole ribonucleotide mutase	protein	159	48% helix, 16% strand	Q2QJL3
B	N5-carboxyaminoimidazole ribonucleotide mutase	protein	160	48% helix, 14% strand	Q2QJL3

Pockets

2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	63	0.32	0.76	18	empty
2	53	0.29	0.75	14	empty

Interfaces

1 interface between chains.

A–B · 1653 Å² buried · 29 hydrogen bonds · protein-protein

Compared structures

2FW8 · Structure of PurE (N5-carboxyaminoimidazole ribonucleotide mutase) H89G from the… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q2QJL3
Elsewhere: RCSB PDB 2FW8 · PDBe 2FW8 · UniProt Q2QJL3

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