Research workbench

Structure of the yeast SIR3 bah domain

Analyse Structure of the yeast SIR3 bah domain in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 2FVU
Type: protein
Length: 381 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Regulatory protein SIR3
UniProt: P06701
Pockets: 1 · best druggability 0.68

Structure

x-ray diffraction · 2 distinct chains · 29% helix, 38% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Regulatory protein SIR3	protein	190	29% helix, 38% strand	P06701
B	Regulatory protein SIR3	protein	191	29% helix, 38% strand	P06701

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	656	0.68	0.76	53	empty

Interfaces

1 interface between chains.

A–B · 1163 Å² buried · 26 hydrogen bonds · protein-protein

Compared structures

2FVU · Structure of the yeast Sir3 BAH domain · the same entry in another collection · chain A against A, TM-score 1.00
P06701 · AlphaFold monomer V2.0 prediction for regulatory protein SIR3 (P06701) · a predicted model of the same protein · chain B against A, TM-score 0.94

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P06701
Elsewhere: RCSB PDB 2FVU · PDBe 2FVU · UniProt P06701

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.