Research workbench
Phage PHI29 transcription regulator P4
Analyse Phage PHI29 transcription regulator P4 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 2FIP
- Type
- protein
- Length
- 685 residues
- Chains
- 6
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Late genes activator
- UniProt
- P03682
- Pockets
- 5 · best druggability 0.72
Structure
x-ray diffraction · 3 distinct chains · 44% helix, 14% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B, C, E | Late genes activator | protein | 115 | 43% helix, 15% strand | P03682 |
| D | Late genes activator | protein | 114 | 45% helix, 13% strand | P03682 |
| F | Late genes activator | protein | 111 | 46% helix, 14% strand | P03682 |
Pockets
5 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 57 | 0.72 | 0.98 | 20 | empty |
| 2 | 61 | 0.71 | 0.97 | 22 | empty |
| 3 | 126 | 0.45 | 0.78 | 23 | empty |
| 4 | 124 | 0.37 | 0.73 | 21 | empty |
| 5 | 61 | 0.30 | 0.75 | 19 | empty |
Interfaces
6 interfaces between chains.
- C–D · 901 Ų buried · 1 hydrogen bond · protein-protein
- E–F · 852 Ų buried · 1 hydrogen bond · protein-protein
- A–B · 822 Ų buried · 0 hydrogen bonds · protein-protein
- A–C · 383 Ų buried · 4 hydrogen bonds · protein-protein
- B–F · 61 Ų buried · 0 hydrogen bonds · protein-protein
Compared structures
- 2FIP · Phage phi29 transcription regulator p4 · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P03682
- Elsewhere: RCSB PDB 2FIP · PDBe 2FIP · UniProt P03682
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