Research workbench
The crystal structure of human neuronal RAB6B in its active gtpgs-bound form
Analyse The crystal structure of human neuronal RAB6B in its active gtpgs-bound form in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 2FFQ
- Type
- protein
- Length
- 164 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- RAS-related protein rab-6B
- EC
- 3.6.1.-
- UniProt
- Q9NRW1
- Ligands
- GSP, MG
- Pockets
- 1 · best druggability 0.60
Structure
x-ray diffraction · 1 distinct chain · 40% helix, 26% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | RAS-related protein rab-6B (EC 3.6.1.-) | protein | 164 | 40% helix, 26% strand | Q9NRW1 |
Ligands and binding sites
- GSP · 5'-guanosine-diphosphate-monothiophosphate · ligand · chains A
- MG · Magnesium ion · metal · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 183 | 0.60 | 0.82 | 31 | MG, GSP |
Compared structures
- 2FFQ · The crystal structure of human neuronal Rab6B in its active GTPgS-bound form · the same entry in another collection · chain A against A, TM-score 1.00
- Q9NRW1 · AlphaFold monomer V2.0 prediction for RAS-related protein rab-6B (Q9NRW1) · a predicted model of the same protein · chain A against A, TM-score 0.98
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9NRW1
- Elsewhere: RCSB PDB 2FFQ · PDBe 2FFQ · UniProt Q9NRW1
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