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Crystal structure of the processivity clamp GP45 from bacteriophage T4

Analyse Crystal structure of the processivity clamp GP45 from bacteriophage T4 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 1CZD
Type: protein
Length: 684 residues
Chains: 3
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: DNA polymerase accessory protein G45
UniProt: P04525
Pockets: 8 · best druggability 0.45

Structure

x-ray diffraction · 1 distinct chain · 19% helix, 40% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B, C	DNA polymerase accessory protein G45	protein	228	19% helix, 40% strand	P04525

Pockets

8 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	189	0.45	0.74	24	empty
2	130	0.40	0.74	22	empty
3	58	0.37	0.79	19	empty
4	87	0.34	0.74	17	empty
5	59	0.33	0.77	13	empty

Interfaces

3 interfaces between chains.

A–B · 457 Å² buried · 8 hydrogen bonds · protein-protein
B–C · 449 Å² buried · 7 hydrogen bonds · protein-protein
A–C · 427 Å² buried · 7 hydrogen bonds · protein-protein

Compared structures

1CZD · Crystal structure of the processivity clamp GP45 from bacteriophage T4 · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P04525
Elsewhere: RCSB PDB 1CZD · PDBe 1CZD · UniProt P04525

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