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Crystal structure of oxidized form from saccharomyces cerevisiae

Analyse Crystal structure of oxidized form from saccharomyces cerevisiae in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 2FA4
Type: protein
Length: 208 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Thioredoxin II
UniProt: P22803
Pockets: 1 · best druggability 0.33

Structure

x-ray diffraction · 1 distinct chain · 39% helix, 29% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	Thioredoxin II	protein	104	39% helix, 29% strand	P22803

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	57	0.33	0.77	14	empty

Interfaces

1 interface between chains.

A–B · 436 Å² buried · 6 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 2 disulfide (disulfide).

Compared structures

2FA4 · Crystal Structure of Oxidized Form from Saccharomyces cerevisiae · the same entry in another collection · chain A against A, TM-score 1.00
P22803 · AlphaFold monomer V2.0 prediction for thioredoxin-2 (P22803) · a predicted model of the same protein · chain A against A, TM-score 0.99

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P22803
Elsewhere: RCSB PDB 2FA4 · PDBe 2FA4 · UniProt P22803

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