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Catm effector binding domain

Analyse Catm effector binding domain in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 2F7B
Type: protein
Length: 214 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Hth-type transcriptional regulator catm
UniProt: P07774
Ligands: SO4, CL
Pockets: 3 · best druggability 0.50

Structure

x-ray diffraction · 1 distinct chain · 32% helix, 28% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Hth-type transcriptional regulator catm	protein	214	32% helix, 28% strand	P07774

Ligands and binding sites

SO4 · Sulfate ion · ion · 4 copies · chains A
CL · Chloride ion · ion · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

3 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	71	0.50	0.84	19	empty
2	107	0.47	0.80	24	SO4, CL
3	51	0.25	0.73	17	SO4

Compared structures

2F7B · CatM effector binding domain · the same entry in another collection · chain A against A, TM-score 1.00
P07774 · AlphaFold monomer V2.0 prediction for hth-type transcriptional regulator catm (P07774) · a predicted model of the same protein · chain A against A, TM-score 0.97

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P07774
Elsewhere: RCSB PDB 2F7B · PDBe 2F7B · UniProt P07774

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